This project aims to create a trivalent vaccine to reduce photobacteriosis outbreaks in farmed Yellowtail Kingfish (reported in association with Photobacterium damselae subsp damselae (Pdd), Photobacterium damselae subspecies piscicida(Pdp) and various Vibrio harveyi(Vh) isolates).

It will do this by:

• generating a comprehensive genome database of Australian isolates of Pdd, Pdp and Vh associated with Photobacteriosis outbreaks in Yellowtail Kingfish (YTK);
• creating diagnostic laboratory reagents and methods for typing Photobacterium and Vibrio isolates associated with YTK outbreaks; and
• delivering optimised monovalent and multivalent (Pdd, Pdp, Vh) killed vaccines, with production outline, appropriate adjuvant type, dose, safety and efficacy profile in YTK, ready for manufacture.