Skip to Content Skip to Navigation

Metabolism study to determine the quantity and identify the nature of parent compounds and metabolites in ovine tissue and fluids following the topical administration of Tri-Solfen

Mulesing, tail docking, and castration are animal husbandry procedures conducted on farm as part of routine management. Tri-Solfen is used in Australian sheep industries for the provision of pain relief and to assist wound healing in lambs undergoing mulesing, tail docking, and castration. The data obtained from this study will allow better characterisation of residues in edible tissues and provide an understanding of the metabolism profiles of each of the three active ingredients in Tri-Solfen (lignocaine, bupivacaine and cetrimide), and provide supportive data for the definition of the withholding period (WHP) and export slaughter interval (ESI) for Tri-Solfen in lambs when applied topically. Results from this work have been provided to pharmaceutical companies for their use in applications to the APVMA.

Project date

7 Aug 2014-30 Jun 2019

Principal investigator

Dr Brendan Sharpe / Dr Ruth Davis

Research organisations

Invetus Proprietary Limited
Redcap Solutions Pty Ltd
Veterinary Health Research Pty Ltd

Project led by

Multiple industries
Other rural industries Sheep Wool

Australian Wool Innovation (AWI)

Australian Wool Innovation is a not-for-profit enterprise that conducts research, development and marketing along the worldwide supply chain for Australian …

Multiple industries
Other rural industries Sheep Wool
  • Location

    Australia wide

  • Organisation type

    Research funding body

Logo for Australian Wool Innovation (AWI)

Focus areas

Industries

Sustainabilities

Technology areas

Related research projects

Search all research projects
Logo for Feedbase Advisory Panel
Multiple industries

Feedbase Advisory Panel

The AWI Feedbase Advisory Panel aim is to review previous feedbase research projects, investigate the barriers to adoption and set …
  • Led by

    Australian Wool Innovation (AWI)

  • Start date

    14 Aug 2018

  • Research organisation

    Australian Wool Innovation (AWI)

Logo for Australian Pastures Genebank
Multiple industries

Australian Pastures Genebank

The Australian Pastures Genebank (APG) Phase 1 was established in 2013 and operates under the framework of the International Treaty on Plant …
  • Led by

    Australian Wool Innovation (AWI)

  • Start date

    1 Jul 2019

  • Research organisation

    South Australian Research and Development Institute (SARDI)

Logo for CRSPI 2018-2020
Multiple industries

CRSPI 2018-2020

The Climate Research Strategy for Primary Industries (CRSPI) is a partnership between Australian research organisations to invest in climate research, …
  • Led by

    Australian Wool Innovation (AWI)

  • Start date

    1 Jan 2019

  • Research organisations

    AgriFutures Australia, Australian Pork (APL)

Have questions?

Find out how we can help you.

Find answers to our most frequently asked questions on research projects, commercial opportunities, organisations and more. 

Still have questions or have feedback on the site? Please get in touch by completing our enquiry form.